Published: 30th October 2010
DOI: 10.4204/EPTCS.40
ISSN: 2075-2180


Proceedings Fourth Workshop on
Membrane Computing and Biologically Inspired Process Calculi 2010
Jena, Germany, 23 August 2010

Edited by: Gabriel Ciobanu and Maciej Koutny

Gabriel Ciobanu and Maciej Koutny
Stochastic Simulation of Process Calculi for Biology
Andrew Phillips, Matthew Lakin and Loïc Paulevé
Measurable Stochastics for Brane Calculus
Giorgio Bacci and Marino Miculan
An Abstraction Theory for Qualitative Models of Biological Systems
Richard Banks and L. Jason Steggles
Computational Modeling for the Activation Cycle of G-proteins by G-protein-coupled Receptors
Yifei Bao, Adriana Compagnoni, Joseph Glavy and Tommy White
Aspects of multiscale modelling in a process algebra for biological systems
Roberto Barbuti, Giulio Caravagna, Paolo Milazzo, Andrea Maggiolo-Schettini and Simone Tini
Multiscale Bone Remodelling with Spatial P Systems
Diletta Cacciagrano, Flavio Corradini, Emanuela Merelli and Luca Tesei
Modeling biological systems with delays in Bio-PEPA
Giulio Caravagna and Jane Hillston
Hybrid Calculus of Wrapped Compartments
Mario Coppo, Ferruccio Damiani, Maurizio Drocco, Elena Grassi, Eva Sciacca, Salvatore Spinella and Angelo Troina
Edge- and Node-Disjoint Paths in P Systems
Michael J. Dinneen, Yun-Bum Kim and Radu Nicolescu
Lumpability Abstractions of Rule-based Systems
Jerome Feret, Thomas Henzinger, Heinz Koeppl and Tatjana Petrov
Qualitative modelling and analysis of regulations in multi-cellular systems using Petri nets and topological collections
Jean-Louis Giavitto, Hanna Klaudel and Franck Pommereau


This issue of EPTCS contains revised and extended versions of papers from the 4th Workshop on Membrane Computing and Biologically Inspired Process Calculi (MeCBIC 2010) held at the 11th International Conference on Membrane Computing (CMC11), Jena, Germany, 23 August 2010.

Biological membranes play a fundamental role in the complex reactions which take place in cells of living organisms. The importance of this role has been considered in two different types of formalisms introduced recently. Membrane systems were introduced as a class of distributed parallel computing devices inspired by the observation that any biological system is a complex hierarchical structure, with a flow of biochemical substances and information that underlies their functioning. The modeling and analysis of biological systems has also attracted considerable interest of the process algebra research community. Thus the notions of membranes and compartments have been explicitly represented in a family of calculi, such as Ambients and Brane Calculi. A cross fertilization of these two research areas has recently started. A deeper investigation of the relationships between these related formalisms is interesting, as it is important to understand the crucial similarities and the differences.

The main aim of the MeCBIC 2010 was to bring together researchers working on membrane computing, in biologically inspired process calculi, and in other related fields, in order to present recent results and to discuss new ideas concerning such formalisms, their properties and relationships. In the call-for papers, original research papers (including significant work-in-progress) on the membrane systems or biologically inspired process calculi had been sought. All submitted papers were reviewed by three or four referees. As a result, 10 papers were accepted for presentation at the workshop, and we thank the reviewers and authors for doing an outstanding job.

We are also indebted to the members of the Programme Committee: Joern Behre (Germany), Luca Cardelli (United Kingdom), Matteo Cavaliere (Spain), Federica Ciocchetta (Italy), Flavio Corradini (Italy), Erzsebet Csuhaj-Varju (Hungary), Erik de Vink (Netherlands), Marian Gheorghe (United Kingdom), Jean-Louis Giavitto (France), Thomas Hinze (Germany), Paolo Milazzo (Italy), Angelo Troina (Italy), Claudio Zandron (Italy), Gianluigi Zavattaro (Italy). Without their enthusiastic work this volume would not have been possible.

We wish to express our gratitude to the invited speaker Andrew Phillips for his lecture on stochastic simulation of process calculi. Finally, we would like to thank Friedrich Schiller Universität for hosting the workshop and providing financial support, and to Rob van Glabbeek for his kind help in preparing this volume.

Gabriel Ciobanu and Maciej Koutny
Program Committee Chairs, MeCBIC 2010